Themes based on photoshop designs

Hello, I have a question as a relatively new Drupal user (and enthusiast). Like many, I learned web design from making a "camera ready" mock-up in photoshop and then slicing it up and rebuilding the slices in a program like GoLive.... I still love the visual flexibility this gives me to come up with any "look" that I want.

So I would be very interested in some information for integrating this design approach with Drupal themes. For example, is anyone else creating Photoshop designs and then making custom themes from them? Is there any way to build a theme with photoshop slices? I'm just testing the waters here - it seems like someone must be doing this.... Any kind of tutorials or step-by-step instructions (pointed toward newbies) along these lines would be very appreciated!

Thanks,

Jim