|Component:||In-Place Editor (IPE)|
Clean install of D7, panels, ctools. Enabled page_manager, panels, and panels_ipe.
I enabled the node view panel page, set up a variant for the article node type that comes with core, and added the node content to one pane.
Then from the node page itself, using the IPE, I added the field_image field to another pane, and hit save.
The page looses its content, the IPE bar at the bottom still shows. A regular refresh shows the content was changed correctly.
Nothing in watchdog, or JS console. Notices are set to display.