Make spamspan work in profile fields

Spamspan is a filter, and uses Drupal's filter capability to interecept emails in text entered by the user. The problem here is that fields added using the core profile module (which is what I guess you are talking about), are not passed by Drupal through the filters (with the exception I think of multi-line text fields). So it is not straighforward to do what you want (though I suspect it is possible using hook_profile_alter). You could try (1) using a multi-lline textfield for the entry of email addresses, or (2) raising an issue against the profile module. I will think about whether it is something that might be useful as an optional extra for the spamspan module.

Profile is now deprecated. Closing.