In the .info file I added to the bottom of the list of stylesheets file.css and added some rules in this file. I quoted the selectors (id's and classes) that I was able to identify with firebug. when using these id's and classes with firebug the changes took effect. however, when I upload the new file.css to my theme no changes take place.
All caches cleared.
The site uses panels module and the content I am trying to effect is presented via panel.