Step 2: Gallery2 location settings - Manual Configuration

I have attempted to use the URL, relative path and direct path and I still get this "Everything seemed OK, but the Gallery could still not be initialised. Perhaps a manually entered value is incorrect." I am not sure why but the Gallery2 install works fine and so does Drupal. It appears that it sees the Gallery2 installed but can't start it? Can you shed any light on this?

Albatros