We just launched our first Drupal website for the Asia Pacific Foundation of Canada (http://asiapacific.ca). The foundation was looking to move from a very old Coldfusion setup that required IT staff to manage to a system that their in house staff could largely handle. We chose Drupal as our platform and helped them move over a several thousand documents of various types from their old site to their new one.
The site is partially bilingual as some sections have both French and English content (eg. About Us, Media Centre) and this proved to be very challenging as we had to make accommodation for various pieces of text that were available in both languages.
Being our first site we ran into a number of challenges just from our general newness to Drupal but all in all, we are very happy with the choice we made with Drupal and we plan on using it for a lot of future projects. Any and all feedback is appreciated.
Eric