Reconfiguring a block region

So, I've got front_page going on my site. Thing is, I want to set up a block region so that it displays blocks in horizontal rows, starting a new row when it runs out of space. I've got a thing going right now where I set the blocks for the region with the attribute float: left, but that creates a lot of ... ahem ... interesting permutations across browsers when it comes to display. Any ideas how to make it work?

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