Mailing members based on common profile field

I was wondering:

right now i use the mail.module to email members by role

That's fine but there is a need for mailing members based on common data such as:

- all members that are from one country or region of that country (state)
- all members that are (fe)male
etc

These self created profile fields (profile module) will allow me to look up public fields in the profile that have common data and will give me multiple pages of (e.g.) all from NJ.

Is there a way to have members and mail and profile modules work together that the above is possible?

Thanx