"Customer Management System"
Is there a module(s) already in place, for webmasters, for managing requests from customers to do work on their sites? I build all my customers sites using Drupal (won't do it any other way), and want to set up a system where they can log in and submit requests for work, and I will have a 'work queue' to manage the requests and jobs. We used a 'Remedy" system when I worked for Xerox to do this for work requests for printer repair, and I want to set up something similar for my business (Galveston County Websites - www.galcowebs.com). If someone else has not thought of this already (would surprise me), I will develop and contribute it to the community, as this would help any web designer managing large numbers of sites. Thanks to all!
"Open source is the LOGICAL way to go!"

...GalCo found Storm
...stumbled across Storm, which looks at quick glance to be close if not it. I am checking it out....
Ticketing system
Sounds like you're looking for a ticketing system, not a CRM. See http://groups.drupal.org/node/17948
On the theory that Simple is Good, we're using the Drupal project and project issue modules for our Drupal-related work. We're getting rid of Remedy, and glad to do it.
Also Within Drupal
OpenAtrium was originally built as an in-house extranet for Development Seed, so out of the box it has casetracker functionality.
Also, it's pretty easy to build a case tracker using Comment CCK and Views.