diff --git a/apc.module b/apc.module
index e29c9e0..f14f8da 100644
--- a/apc.module
+++ b/apc.module
@@ -1,4 +1,49 @@
 <?php
+/**
+ * Implements hook_xmlrpc().
+ */
+function apc_xmlrpc() {
+  $methods[] =  array(
+    'apc_drush_flush', // Method name.
+    'apc_drush_flush', // Callback.
+    array(
+      'array', // Return variable.
+      'array', // Input variable.
+    ),
+    t('XMLRPC callback to enable cache clear from Drush/CLI.'), // Description
+  );
+
+  return $methods;
+}
+
+/**
+ * XMLRPC callback to enable cache clear from Drush/CLI.
+ */
+function apc_drush_flush($variables) {
+  $cron_key = isset($variables['cron_key']) ? $variables['cron_key'] : NULL;
+  $caches = isset($variables['caches']) ? $variables['caches'] : array();
+
+  if (empty($cron_key) || variable_get('cron_key', 'drupal') != $cron_key) {
+    watchdog('apc', 'APC could not flush cache(s) because an invalid key was used.', array(), WATCHDOG_ERROR);
+    return array(
+      'success' => FALSE,
+      'message' => t('APC could not flush cache(s) because an invalid key was used.'),
+    );
+  }
+  else {
+    foreach ($caches as $cache) {
+      list($bin, $cid, $wildcard) = explode('|', $cache);
+
+      $apc = _cache_get_object($bin);
+      $apc->clear($cid, $wildcard == 1);
+    }
+
+    return array(
+      'success' => TRUE,
+      'message' => t('APC bin "@bin" flushed', array('@bin' => $bin)),
+    );
+  }
+}
 
 /**
  * Implementation of hook_init().
diff --git a/drupal_apc_cache.inc b/drupal_apc_cache.inc
index 2f7e330..c0e453f 100644
--- a/drupal_apc_cache.inc
+++ b/drupal_apc_cache.inc
@@ -38,6 +38,16 @@ class DrupalAPCCache implements DrupalCacheInterface {
   protected $prefix;
 
   /**
+   * @var array
+   */
+  protected $drush_flush;
+
+  /**
+   * @var boolean
+   */
+  protected $drush;
+
+  /**
    * Get prefix for bin using the configuration.
    *
    * @param string $bin
@@ -75,6 +85,7 @@ class DrupalAPCCache implements DrupalCacheInterface {
 
   function __construct($bin) {
     $this->bin = $bin;
+    $this->drush = (drupal_is_cli() && function_exists('drush_log'));
 
     // First we determine the prefix from a setting.
     $prefix = self::getPrefixSettingForBin($this->bin);
@@ -101,6 +112,38 @@ class DrupalAPCCache implements DrupalCacheInterface {
     $this->prefix = $prefix;
   }
 
+  function __destruct() {
+    if (!$this->drush) {
+      return;
+    }
+
+    if (!empty($this->drush_flush) && isset($GLOBALS['conf']['apc_nodes']) && !empty($GLOBALS['conf']['apc_nodes'])) {
+      foreach ($GLOBALS['conf']['apc_nodes'] as $apc_node) {
+        $args = array(
+          'apc_drush_flush' => array(array(
+            'caches' => $this->drush_flush,
+            'cron_key' => variable_get('cron_key', 'drupal'),
+          )),
+        );
+        $uri = $apc_node . '/xmlrpc.php';
+        $response = xmlrpc($uri, $args);
+
+        if (!is_array($response)) {
+          drush_log($response, 'error');
+        }
+        elseif (!$response['success']) {
+          drush_log('APC could not flush cache(s) because ' . $apc_node . ' returned code ' . $response['message'], 'error');
+        }
+        else {
+          drush_log($response['message'], 'success');
+        }
+      }
+    }
+    else {
+      drush_log('@todo', 'warning'); // @todo: add some sane errors
+    }
+  }
+
   /**
    * Function which retrieves the safe key for the cache bin.
    *
@@ -254,8 +297,8 @@ class DrupalAPCCache implements DrupalCacheInterface {
   }
 
   function clear($cid = NULL, $wildcard = FALSE) {
-    if (drupal_is_cli() && function_exists('drush_log')) {
-      drush_log($this->bin . '(' . $cid . ') was not cleared. APC cli uses a different memory storage then the webserver. For more info see: http://drupal.org/node/1278232', 'warning');
+    if ($this->drush) {
+      $this->drush_flush[] = implode('|', array($this->bin, $cid, $wildcard));
       return;
     }