In admin/config/development/performance , choosing Javascript aggregation option has the effect that all CKEditor buttons disappear from all content edit pages.

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I have the same problem - does anyone know how to fix this?

I am having the same issue, whenever I check aggregate JavaScript under performance CKEditor and other WYSIWYG editors disappear. What i also find is many of the items which before in the admin theme that where hidden or minimised are now unhidden, and some of the administration panel items, such as editing a user is now far longer in comparison. What would cause all this to heppen, to me this appears to prevent all JavaScript from running correctly.