Taxonomy in user and in node; is there a way to filter?

I have certain user that are specified as sales people. Each sales person has a subset of taxonomy terms that are based on regions on a map. Most have 5 or more regions. The nodes that contain the same regions from the same taxonomy have only one of the taxonomy regional terms.

Another complicating issue is that the view is being shown at the user's profile using a proper path and menu type. The filter is not to be based on the logged in user but the user profile being viewed.

Example:

The users with a 'sales role' will only be able to see their own profile. A 'manager role' will be able to see all profiles so that they can manage the nodes, the regions and the users. When those managerial users look at a profile and open the view they must see only the nodes filtered by that user's profile region taxonomy.

My search for a solution has become mired in so may postings for views and taxonomy. Thanks in advance for any suggestions on how to approach this or where I might even begin to narrow my search for a solution.